By George M. Rodgers
This accomplished quantity discusses the protease ADAMTS13, summarizing the present prestige of simple and scientific examine. The 9 authoritative chapters start with a ancient standpoint via exploration of the biochemistry and structure-function relationships of ADAMTS13 in addition to its basic functionality in hemostasis (cleavage of von Willebrand factor). rising study topics for ADAMTS13 are coated, together with its power position in angiogenesis and different elements of cellphone biology. extra subject matters contain laboratory assays for ADAMTS13, inherited ADAMTS13 deficiency, and bought ADAMTS13 deficiency. A bankruptcy on comparable thrombotic microangiopathic (TMA) problems examines the variations among TMAs linked to ADAMTS13 deficiency and people now not linked to ADAMTS13 deficiency. a last bankruptcy stories the initial info on rising features of ADAMTS13, corresponding to the prestige of recombinant ADAMTS13 items and their strength utility.
Comprehensive in its exploration of the ADAMTS13 protease in disease, ADAMTS13: Biology and affliction is an important source for scientific hematologists, transfusion drugs physicians, and researchers drawn to hemostasis, vascular biology, biochemistry, and metalloproteases.
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Extra resources for ADAMTS13: Biology and Disease
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