Actin-based Motility: Cellular, Molecular and Physical by J. Victor Small, Klemens Rottner (auth.), Marie-France

By J. Victor Small, Klemens Rottner (auth.), Marie-France Carlier (eds.)

This e-book provides the mobile, molecular and actual elements of strength and flow by means of the self-assembly of actin, essentially the most plentiful proteins present in cells, into cytoskeletal filaments. « Actin-based motile methods » are answerable for a wide number of motile actions equivalent to chemotactic locomotion, embryonic and metastatic mobile migration, wound therapeutic, eukaryotic cytokinesis and bacterial plasmid segregation, endocytic and phagocytic actions, in addition to morphogenetic procedures together with, axis patterning in early embryos, axonal progress in mind improvement, and the immune reaction and synaptic plasticity techniques on the starting place of studying and reminiscence. The booklet describes how the lately undertaken multidisciplinary and multiscale methods have explored the molecular and actual mechanisms on the starting place of strength and move produced by way of actin self-assembly. the selected subject matters exhibit how advances were made within the box of telephone motility as a result of growth in dwell mobilephone imaging, gentle microscopy, more desirable solution within the constitution of huge protein assemblies, the biochemical research and mathematical modeling of actin meeting dynamics and the improvement of nanotechnologies permitting us to degree forces within the variety of pico- to nano-newtons produced via actin assemblies.

Show description

Read or Download Actin-based Motility: Cellular, Molecular and Physical Aspects PDF

Similar physical books

Forensic Recovery of Human Remains: Archaeological Approaches, Second Edition

This reference, now in its moment variation, is a complete consultant that specializes in the sensible elements of excavating and recuperating human continues to be, in addition to any linked facts, from crime scenes. It highlights the protocols and strategies which are used to effectively survey, map, get well, rfile, acquire, and delivery proof.

The Physical Environment and Behavior: An Annotated Bibliography and Guide to the Literature

The sector of "Environment-and-Behavior" This bibliography is aimed toward the researcher and complicated scholar operating within the box of environmental psychology, because it has grow to be specific during the last decade. A extra acceptable time period may be "environment-behavior studies," to signify the $64000 attribute of this box as person who transcends the province of the psychologist, and brings jointly employees, in addition to difficulties, tools, and ideas from an exceptional range of disciplines fields.

Physical Methods in Heterocyclic Chemistry: Volume IV

Actual equipment in Heterocyclic Chemistry, quantity IV, discusses the appliance of actual the way to natural chemistry, and particularly to heterocyclic chemistry. because the booklet in 1963 of the 1st volumes of this treatise, the appliance of actual how you can natural chemistry, and particularly to heterocyclic chemistry, has proceeded apace.

Additional resources for Actin-based Motility: Cellular, Molecular and Physical Aspects

Sample text

Lorenz, S. Kempiak, C. Sarmiento, S. Coniglio, M. Symons, J. Segall, R. Eddy, H. Miki, T. Takenawa, and J. Condeelis. 2005. Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin. J Cell Biol. 168: 441–52. , L. Czech, S. Gerboth, S. Kojima, G. Scita, and T. Svitkina. 2007. Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells. PLoS Biol. 5:e317. , and T. Soldati. 2006. Dissection of amoeboid movement into two mechanically distinct modes.

Polymerization of actin. VI. The polarity of the actin filaments in the acrosomal process and how it might be determined. J Cell Biol. 81:608–23. , C. Sykes, and J. Plastino. 2008. Relaxing the actin cytoskeleton for adhesion and movement with Ena/VASP. J Cell Biol. 181:19–25. P. 1984. Cells into organs: the forces that shape the embryo. Prentice Hall, Upper Saddle River, NJ. , I. Weber, D. C. R. Soll, G. A. Titus. 2001. A role for myosin VII in dynamic cell adhesion. Curr Biol. 11:318–29. , S.

Vale. 2003. Molecular requirements for actinbased lamella formation in Drosophila S2 cells. J Cell Biol. 162:1079–88. , B. V. Small, and J. Wehland. 1999a. VASP dynamics during lamellipodia protrusion. Nat Cell Biol. 1:321–22. , A. V. Small. 1999b. Interplay between Rac and Rho in the control of substrate contact dynamics. Curr Biol. 9:640–48. J. Marshall. 2003. Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat Cell Biol.

Download PDF sample

Rated 4.48 of 5 – based on 49 votes