By Hans G. Drexler
This e-book represents a vital reference handbook for the entire well-characterized leukemia-lymphoma telephone strains at present to be had. It presents an important evidence, utilizing the succinct and undemanding structure that has made the FactsBooks so well liked by scientists and scientific researchers. Introductory chapters supply historical past and viewpoint for culturing malignant hematopoietic (blood forming) telephone traces. those chapters are by way of over four hundred accomplished person entries. each one mobile line access highlights crucial scientific, immunological, genetic, and sensible good points and encompasses a entire directory of references.
* the entire spectrum of malignant cellphone traces from all hematopoietic telephone lineages
* sister cellphone traces and suitable subclones
* medical info: sufferer, analysis, remedy prestige, and specimen source
* authentication of derivation and availability
* cytogenetic karyotype
* translocations and fusion genes
* receptor gene rearrangements and genetic alterations
* mobilephone cultures facets: institution, medium, doubling time, growth
* cytochemical profile
* cytokine construction and reaction to cytokines
* proto-oncogene and transcription issue expression/alteration
* useful positive aspects: differentiation induction, heterotransplantability
* certain specific features
* key references
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